Reviewed by Dr Roy Kedem, MD
Information last reviewed 09/25/20
Clotrimazole is an antifungal medication which is effective against yeast infections. Yeast infections, including thrush, are caused by the fungus Candida Albicans. Symptoms of thrush include:
When the Candida fungus proliferates it causes yeast infections. Candida normally lives in the body without causing problems e.g. in the gut, but when it grows too quickly it can be harmful and cause an infection. Many different factors can precipitate this including antibiotics stress and excessive moisture, which create favorable conditions for Candida to grow. The common symptoms outlined above for thrush can be a cause of discomfort. It is important to get treated to avoid complications like further infection, fatigue, and recurrence.
When Candida albicans proliferates, it can cause a yeast infection. Candida normally lives in the body without causing problems (e.g. in the gut), but when it multiplies too quickly, it can be harmful and cause an infection. Many different factors can precipitate this, including antibiotics, stress, excessive moisture and corticosteroid use, which can create favorable conditions for Candida to grow. Additionally, individuals with underlying medical issues such as diabetes or any condition affecting the immune system, may be more prone to developing thrush.
Thrush is normally a superficial infection, however, left untreated it can cause significant complications. Complications of thrush, although uncommon in healthy individuals, may include bacterial skin infections or an infection which invades the blood, valves of the heart and even the brain.
Clotrimazole kills the yeast, Candida, by creating holes in its cell membrane. This causes the contents of the cell to leak out and the yeast to die. As a result, the infection clears up.
Normally your thrush should clear within 1 week. Make sure you use the medicine regularly as advised to ensure the best chance of treatment success.
The active ingredient in Clotrimazole cream is Clotrimazole 1%
Clotrimazole-Betamethasone cream contains Clotrimazole 1%, Betamethasone 0.05% as the active ingredients.
Inactive ingredients can vary between different manufacturers. The inactive ingredients in Canesten's Clotrimazole cream are benzyl alcohol, polysorbate 60, sorbitan stearate, cetyl palmitate, cetostearyl alcohol, octyldodecanol and purified water.
Remember to check the label before use and before use ensure you are free of allergies to the ingredients.
In very rare cases, there has been a severe allergic reaction to this cream. The symptoms of a severe allergic reaction are as follows: struggling to breathe, a newfound rash on the body, swelling in the body, or dizziness. Get immediate medical attention if you notice these symptoms. A few inactive ingredients in the cream are alcohols which can cause you some local inflammation and reddening of the skin the cream is applied to.
You should always follow your doctor's instructions when using any prescription treatment. For Clotrimazole, generally, you should:
Remember to apply the medicine as directed by your doctor. To get the most from your treatment wash your hands after application as this will help avoid the spread of infection to other parts of your body. See the bottom of our Q&A section for our other top tips.
We recommend that you continue the treatment for one week after the rash has resolved. This ensures the yeast is completely cleared and the infection is unlikely to reoccur.
Do not worry if this happens. Apply as soon as you remember and then stick to your normal schedule of application.
Side effects are uncommon when using Clotrimazole cream. Possible side effects of Clotrimazole cream include:
If you experience any of these side effects, you should speak to your doctor. Seek immediate medical attention if you experience any severe side effects. It is also possible to have a severe allergic reaction (anaphylaxis) in response to Clotrimazole. If you experience any of these symptoms you should seek immediate medical attention or call an ambulance:
For a full list of side effects refer to the patient information leaflet inside the medicine packet.
There are no known problems with using other medication alongside Clotrimazole creams. However, inform your doctor about any other over-the-counter medication, vitamins and herbal products you are taking.
Do not use this medicine if you are allergic to it. Use as directed and only on the skin.
Here are ways to beat that thrush fast and other top tips:
Clotrimazole cream is an effective treatment for yeast infections, however, there are several things you can do to help:
Both Clotrimazole cream and combination creams using Clotrimazole and a corticosteroid (such as betamethasone) are approved by the FDA. The combination therapy may be useful if you have marked inflammation and soreness of the skin. However, caution must be taken using steroid containing creams on the genitals. They must be used sparingly to avoid skin thinning.
Several brand names exist for Clotrimazole creams. All essentially have the same active ingredient which is clotrimazole. Generics are usually cheaper.
Other antifungal topical treatments are available for example:
While other options are available as mentioned, clotrimazole is commonly used for successfully treating thrush.
No, clotrimazole is an anti-fungal medication, not an antibiotic. Antibiotics treat bacterial infections whereas anti-fungal medications treat fungal infections.
Clotrimazole can be used to treat:
It is sold as a cream, solution or a spray. Which of these is appropriate will depend on where the infection is on your body. The cream can be used for most situations.
It is best to avoid having sex until your infection has cleared because latex products (e.g. condoms and diaphragms) can be weakened by the cream.
Fungal skin infections do not normally clear up without treatment. Even mild infections should therefore be treated, especially if you have other health conditions which affect your immune system.
Disclaimer: This is not medical advice. You and your physician will determine if and how you should take any medication prescribed to you following a medical consultation.
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