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Reviewed by Dr Roy Kedem, MD
Information last reviewed 10/01/20
Montelukast belongs to a family of medications called leukotriene receptor antagonists. They work to reduce the symptoms of asthma and allergies (runny nose, airway narrowing) by blocking these leukotrienes' actions in the body.
Montelukast can be used for several purposes. It can be used to treat mild asthma, exercise-induced asthma, and seasonal allergies (allergic rhinitis).
Montelukast usually works immediately to reduce the leukotriene levels in your body once you have consumed the tablet. However, it might take about a week before the medication reaches full effect.
Montelukast tablets are only available with a doctor's prescription. If you think you benefit from a prescription of Montelukast, simply fill out our consultation form on the Medzino website, and one of our doctors will determine if the medication is suitable for you.
You can get Montelukast tablets from us here at Medzino. Simply fill out our online consultation form. If one of our doctors feels it is safe to prescribe, our pharmacy will ship it in plain discreet packaging right to your door.
Montelukast, brand name Singulair, is made by the company Merck in the USA.
Montelukast is metabolized by the enzyme Cytochrome P450, in the liver. It is excreted into the bile and then into the feces.
The active ingredient is Montelukast sodium. Each 10-mg Singulair tablet contains 10.4mg Montelukast sodium.
Montelukast contains these inactive ingredients: microcrystalline cellulose, lactose monohydrate, croscarmellose sodium, hydroxypropyl cellulose, and magnesium stearate. The tablets are coated in a film that is made up of these ingredients: hydroxypropyl methylcellulose, hydroxypropyl cellulose, titanium dioxide, red ferric oxide, yellow ferric oxide, and carnauba wax.
Unless you are specifically allergic to one of the ingredients, there is not one particular ingredient that is more likely to cause an allergic reaction. However, if you take Montelukast and notice any symptoms of an allergic reaction such as difficulty breathing, face swelling, or hives, stop the medication immediately and get emergency medical attention.
Each Montelukast 10mg tablet should be taken once daily, either in the morning or the evening. You can decide when you will take it. You can take the tablet with or without food. If you miss a dose of the medication, do not worry about the missed dose. Just take the next dose as scheduled normally.
Montelukast 10mg is taken once a day, either in the morning or evening. It is always important to follow the instructions given to you by your healthcare professional and take the medication as prescribed by your doctor. Please do not take a larger dose or use it more frequently.
If you notice any of these side effects, contact your doctor immediately and let them know what you are experiencing.
Montelukast does not usually cause drowsiness or sleepiness. Hence is it perfectly safe to take the tablet in the morning.
There has been no evidence that Montelukast increases blood pressure.
The FDA has released warnings about the link between Montelukast and mental health side effects. Montelukast can cause depression and other mental health side effects. Please make sure to let your healthcare provider know of any mental health conditions you might be suffering from to make sure they prescribe you a safe treatment regimen.
There have been cases of Montelukast increasing body fat and, hence, weight in patients; however, this is rare.
There has been no evidence linking Montelukast and hair loss.
Montelukast interacts with these medications: Gemfibrozil, Loxapine, and Lumacaftor. It is important to let your doctor know of any medicines you take to make sure they are prescribing you a safe treatment. It is also not recommended to consume grapefruit juice while taking Montelukast as it can increase the risk of certain side effects.
At present, there is not sufficient evidence to determine if Montelukast is safe for use during pregnancy. Your doctor will have to weigh the risks and benefits when deciding if Montelukast is suitable for you. It is advised to avoid the use of Montelukast while pregnant if possible.
A study conducted in 2008 concluded that levocetirizine is superior to Montelukast in the treatment of childhood allergic rhinitis. The study was commissioned to compare the efficiency and safety of Montelukast and Levocetirizine in the management of childhood perennial allergic rhinitis.
Zyrtec is the brand name for cetirizine. A study in 2004 found that cetirizine is more effective than Montelukast in reducing the symptoms of allergies such as sneezing, nasal congestion, and rhinorrhea (runny nose).
The Montelukast 10mg tablet is not chewable, but the 4mg and 5mg versions are chewable.
Montelukast is not an antihistamine or a corticosteroid. It belongs to a class of medication called leukotriene antagonists. Antihistamines can also be used to treat allergy symptoms, and inhaled corticosteroids are more commonly used in managing asthma. Topical corticosteroids are used in the treatment of inflammatory skin conditions.
Is it recommended to take Montelukast in the evening if you are using it to treat asthma, determined by a study which concluded that taking Montelukast at night is more effective. However, if Montelukast is used to treat allergies, you can take the tablet either in the morning or evening.
Disclaimer: This is not medical advice. You and your physician will determine if and how you should take any medication prescribed to you following a medical consultation.
Paediatric pulmonary Journal > Montelukast administered in the morning or evening to prevent exercise-induced bronchoconstriction in children https://pubmed.ncbi.nlm.nih.gov/16429427/
UptoDate > Montelukast
Mayo Clinic > Montelukast Oral route https://www.mayoclinic.org/drugs-supplements/Montelukast-oral-route/description/drg-20064902
Pharmacology research and perspective > Adverse drug reactions of montelukast in children and adults https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625152/
Journal of Young Pharmacists > A case of montelukast induced hypercholesterolemia, severe hypertriglyceridemia and pancreatitis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758104/
Pediatric Asthma, Allergy & Immunology Journal > A Comparison of Cetirizine and Montelukast for Treating Childhood Perennial Allergic Rhinitis https://www.liebertpub.com/doi/abs/10.1089/088318704322994958?journalCode=pai#:~:text=Cetirizine%20also%20demonstrates%20more%20substantial,%2C%20eye%20itching%2C%20sneezing%2C%20and
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