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Trimethoprim (generic Bactrim) is frequently used to treat UTIs, as it kills the bacteria quickly and makes you feel better within a day or two.
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Information last reviewed 08/20/19
Trimethoprim is a type of antibiotic. Its main purpose is to treat urinary tract infections (UTIs) but might also be given for chest infections or acne.
Trimethoprim works by stopping the bacteria that causes the infection from being able to multiply and survive, resulting in the disappearance of the bacterial infection.
Your symptoms will usually start to ease off after a few days of starting Trimethoprim. Always complete the full course of the treatment to ensure the infection is properly treated.
The symptoms of a UTI commonly include:
An urgent need to urinate
Frequent urination
Burning feeling or pain while urinating
Urine that's cloudy, smelly or bloody
Lower abdominal pain
Tiredness
In elderly people, they may experience behavioral changes such as confusion and agitation.
The antibiotic is most commonly used for bacterial infections like UTIs. It can also be given to prevent UTIs from recurring in people who get them frequently. Aside from this, the medication can also be useful in the treatment of chest infections and acne.
The active ingredient in Trimethoprim is trimethoprim.
The inactive ingredients in Trimethoprim are colloidal silicon dioxide, lactose, macrogol, magnesium stearate, povidone, sodium starch glycollate, stearic acid, and microcrystalline cellulose (E460). (Please note: inactive ingredients may vary across different manufacturers).
This medication does not contain any active or inactive ingredients associated with causing an allergic reaction in users. However, if you are using the medication for the first time, please lookout for signs of anaphylaxis (facial swelling, difficulty breathing, dizziness, and rash) or a severe skin reaction (burning eyes, sore throat, and fever). If you notice any of these symptoms, please seek immediate medical attention.
If you take too many doses of Trimethoprim, seek immediate medical attention.
You need to take all the doses of Trimethoprim that you have been given otherwise, the infection may not be fully cleared. This leaves you at risk of a repeat UTI.
The dosage may vary depending on your symptoms and the nature of your infection. Always take the dose prescribed by your doctor.
Trimethoprim should be taken at the same time each day, and usually twice daily. Ensure you spread out the doses, taking one pill in the morning and the other in the evening. Each one should be swallowed whole with water.
If you forget a dose of Trimethoprim, take it as soon as you can. If it's nearly time for your second dose then leave the missed one. You should never double up a dose.
Take Trimethoprim for as long as your doctor tells you to. This will vary from one individual to another.
Common side effects include:
Heightened levels of potassium in the blood
Nausea
Vomiting
Diarrhea
Headache
Rash
Urticaria
Anemia
Sore throat
Mouth ulcers
Thrush
Rare side effects may include:
Constipation
Severe diarrhoea
Coughing
Altered behaviour
Aggression
Aseptic meningitis (signs of this include stiff neck, headache, fever, feeling generally unwell, tiredness and sensitivity to light)
Kidney problems
Dizziness
Convulsions
Pins and needles
Shakiness or tremors
Vertigo and tinnitus
Pain or redness in the eyes
Photosensitivity
Low blood sugar
Low sodium
Anorexia
Depression
Anxiety
Insomnia
Confusion
Jaundice
Aching muscles and joints
Shortness of breath
Wheezing
Nosebleeds
Lupus erythematosus
Skin discoloration
Fever
Severe side effects which need immediate medication attention include:
Swollen face, lips, tongue or throat
Difficulty breathing
Chest pain
Fainting or shock
Peeling or blistering of the skin
Lesions or skin eruptions
Pancreatitis
Trimethoprim is not suitable for individuals who:
Are allergic to any of the ingredients in the medicine
Are pregnant
Have a blood disorder
Have severe kidney or liver disease
Tell your doctor if:
You are deficient in folic acid
You have kidney disease
You are having dialysis treatment
The following medications might interact with Trimethoprim:
Other antibiotics
Anticoagulants
Digoxin
Phenytoin
Pyrimethamine
Dapsone
Immunosuppressant drugs
Bone marrow depressants
Spironolactone
Repaglinide
Diuretics
Procainamide
Both Trimethoprim and Nitrofurantoin are antibiotics used to treat UTIs. Nitrofurantoin is used solely for this function as the medicine is filtered straight to the urine. If you have low levels of folic acid in your blood or you are pregnant, then Nitrofurantoin is more suitable. Trimethoprim is likely to be prescribed if you have diabetes or a vitamin B deficiency.
There are several types of antibiotics that treat urinary tract infections. Quinolone types like Nitrofurantoin, Ciprofloxacin, Norfloxacin and Ofloxacin are the first choice of medicines to treat UTIs. Trimethoprim may be prescribed if these types of antibiotics are not suitable, or prove ineffective.
There is no evidence to suggest that alcohol interacts with Trimethoprim. It is considered generally safe to consume alcohol in moderation while taking Trimethoprim.
Other than treating urinary tract infections, Trimethoprim is sometimes used to treat skin and soft tissue infections, Staph infections, certain forms of traveler’s diarrhea, and for the routine prevention of infection in immunocompromised patients.
Trimethoprim is rated as pregnancy category C and is not recommended during the initial 12 weeks of pregnancy, also known as the first trimester. Trimethoprim decreases folic acid levels. Folic acid is very important for the fetus during the first trimester. Lack of folic acid during this time can lead to problems with the unborn baby’s neurological system, known as neural tube defects. Trimethoprim is generally safe after the first trimester.
There are no specific dietary restrictions while taking Trimethoprim. You can take Trimethoprim with or without food. Taking Trimethoprim with food or milk can help ease upset stomach sometimes associated with Trimethoprim and other antibiotics.
No. Although they are both antibiotic pills, they are used to treat different things. They can both be used to treat the common urinary tract infections. Trimethoprim is a “sulfa” antibiotic and works by inhibiting DNA synthesis via a folic acid blocking mechanism. Nitrofurantoin works by blocking bacterial ribosomal function, which blocks their ability to grow.
Disclaimer: This is not medical advice. You and your physician will determine if and how you should take any medication prescribed to you following a medical consultation.
Cystitis is an inflammation of the bladder, usually caused by a common infection of the lower urinary tract. The lower urinary tract comprises the bladder, the urethra (the tube from the bladder which carries urine out), the kidneys, and ureters, which connect the kidneys to the bladder.
Don’t get me wrong, there’s a whole bunch of wonderful things about being a woman, but let’s face it, we’ve all had our moments of resentment at the idea that there are some issues our male counterparts simply don’t have to worry about.
Women are 30 times more likely to get UTIs (urinary tract infections) than men. I know 30 times, that doesn't seem fair. UTIs are not fun, usually painful and inconvenient to daily life. So let's talk. Here's a list of ways to cure STIs and some top tips to prevent them from happening in the first place.
The abdominal pain and burning urination of a UTI is an awful experience and, understandably, you want to get rid of the symptoms as fast as possible. Antibiotics can make this happen within 2-3 days, if, and only if, you make sure to get the right kind of antibiotic. There are many different E. coli bacteria strains that can cause UTIs and some of them are resistant against commonly prescribed antibiotics.
After your doctor has diagnosed you with a urinary tract infection (UTI) the next task is to find out which bacteria has caused the infection. In ~80% of cases the troublemaker is E. coli, but there are about 45 recognized strains of that bacteria species and only about ten of those cause UTIs. Each strain responds in its own way to different antibiotics. Therefore, your doctor will have you do a urine sample test which will be sent to a lab for a urine culture.
So, you just saw a doctor about the pain and burning you experience when peeing and were diagnosed with a urinary tract infection (UTI). Most likely, after testing a urine sample to figure out which bacteria has caused the UTI, your doctor will or already has given you a prescription for antibiotics. How long your antibiotics treatment will be depends on how serious your UTI is. A mild simple UTI may require 2-3 days of antibiotics, but it can go as long as seven days, and complicated UTI may call for a two-week treatment. To ensure that all the bacteria are killed, it’s important that you follow the instructions of your doctor and take the antibiotics as long as prescribed for.
UTIs are infections that typically occur in the urethra, the bladder and — in rare and but potentially fatal cases — in the kidneys. UTIs are among the top three most common infections in the world and over 90% of all UTIs happen to women. This has simple anatomical reasons: it’s much easier for bacteria to enter the vagina and move up the urinary tract. In many cases the troublemaking bacteria come from the woman’s own digestive tract. They go from the anus across the perineum (more commonly known as the “dam”) into the vagina. Another common cause of infection is sex, where bacteria enter the vagina with the partner’s penis.
If you feel a sharp pain in the two sides of your mid to lower back (these are the flanks where the kidneys are) and you experience at least one of the symptoms shown on the list below, it’s quite likely that you have an acute kidney infection (acute pyelonephritis) that requires immediate medical attention. Go see a doctor right away, because if kidney infections are left untreated, they can put your life in danger.
Many women use hygiene products on and in their vaginas on a daily basis, be it soaps, tampons, sprays, or douches. Then there’s a range of birth control devices, such as traditional condoms, internal condoms, and diaphragms, as well as lubes and sex toys. In general, all of the above is well tolerated by most women, especially by women prior to the menopause. But it’s worth discussing the proper use and risks of some of those things we apply to or insert into our vaginas.
When you feel pain or discomfort inside your vagina or in the vulva area in general, or when you notice any unusual discharge or odor that last for longer than a few days, it’s always a good idea to see a doctor. This is because there are several common as well as a couple of rarer vaginal health problems that have similar symptoms and thus are difficult to discern on your own. This is true even if you have previous experience with some of these infections.
As you probably noticed yourself, urinary tract infections (UTI) get better relatively fast once you start taking antibiotics. As the bacteria in the bladder are killed, within the first day of treatment you’ll notice a big improvement in terms of reduced pain and burning. For the bladder to fully recover it will take another 3-4 days after which you should no longer have strong symptoms.
In the United States, urinary tract infections (UTI) account for 6 million patient visits annually, whereas all sexual transmitted infections (STI) amount to around 3 million cases, with roughly 80% of them being for chlamydia, gonorrhea and syphilis. And that’s 3 million for men and women combined, whereas over 90% of the 6 million UTI are women. So, statistically speaking, when you notice something is wrong with your pee or the process of peeing — a burning sensation, pain, strange color or odor — it’s more likely that it’s “just” a UTI. Of course, UTI is a very serious condition in its own right, with risks of complications and chronic reoccurrence, and absolutely requires a doctor’s visit. But it’s probably still better news than an STI.
As you probably know, urinary tract infections (UTI) are one of the most common bacterial infections among women. By the time you reach your mid-30s, there’s on average a 50% chance that you already had at least one UTI in your life so far. The burning pain during urination and constant urge to pee is an unpleasant experience many women are only too familiar with.
UTI are infections of the urinary tract, which includes the urethra, the bladder and the kidneys. The vast majority of UTI registered every year are acute bladder infections (called cystitis in medical speak). They are caused by bacteria entering the vagina, who then move up the urethra (which is the duct between the entrance of your vagina and your bladder) and start multiplying in the bladder. These bacteria most often stem from the E. coli family and can originate from the woman’s own digestive tract (via the anus) or outside sources. Such bacterial infections can result in mild to moderate pain in the bladder, “burning” urine, and an increased urge to urinate. This is what doctors call a “simple UTI.”
UTI is one of the most common infections globally, with around 150 million cases occurring every year. More than 90% of people who get UTI are women and it’s most often seen in the 16-35 age range. That said, women that are experiencing menopause or are in their 60s or older are also at an increased risk, simply because the immune system tends to be a bit weaker at that age. In the vast majority of cases, UTI is a simple acute bladder infection (cystitis) caused by bacteria and treatable with antibiotics. It can be painful and there’s an increased urge to urinate, but there aren’t any more severe symptoms.
UTIs are very common, with some 150 million cases recorded globally in a normal year. Over 90% of patients are women and the ages most at risk are 15 to 35 and any age older than 50. Doctors differentiate between simple UTI, which is an acute cystitis (bladder infection), and complicated UTI which includes chronic UTI, pregnancy related UTI, post-surgery UTI, UTI in patients older than 65, and any UTI where the infection has already advanced to the kidneys. Complicated UTI often need more than just antibiotics to be successfully treated. However, for a simple, acute UTI (i.e., it has only lasted for less than 10 days) antibiotics can be all it takes to effectively treat the infection.
UTI is one of the most frequently seen microbial infections in the world and in a typical year occurs in about 2% of the global population. Some 90% of patients are women. In fact, 50% of all women in the U.S. will have at least one UTI by the time they are 35, and ~20% of women aged 18-24 even experience it annually. The risks of getting UTI is less severe for middle-aged women but the risks rises again in and after menopause. Aside from age, existing diabetes is a risk factor.
While many people who are suffering from cystitis turn to their doctor for a medical treatment, many others prefer to try an alternative bladder infection treatment. Although there’s doubt that a natural bladder infection treatment will work, some of them have been effective, especially when treating mild forms of the condition. However, to best prevent the spread of cystitis, and further complications such as kidney infections, we recommend seeking confirmed medical treatments such as Trimethoprim, Nitrofurantoin and MacroBid. It is possible to use these alternative treatments alongside prescription medications to improve your condition. Here are some of the most popular alternative treatments for bladder infections like cystitis.
While Nitrofurantoin and alcohol do not have any known interactions, it is still not a good idea to mix the two. Moderate alcohol consumption (one glass a day for women and two glasses a day for men) has been shown to have no negative effect on Nitrofurantoin. However, if you drink excessive amounts, it could cause serious health problems and may reduce the drug’s effectiveness.
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