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Propranolol (generic Inderal) is a prescription-only beta-blocker that will lower your blood pressure to healthier levels. It can also be used to treat other conditions, such as irregular heart rhythm.
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Information last reviewed 07/09/20
Propranolol is a medication from the 1st generation beta-blocker class and it’s commonly used to treat heart conditions, such as hypertension (high blood pressure), heart rhythm problems, or circulatory disorders. The drug also is used in the treatment and prevention of heart attack as well as in treating anxiety, angina related chest pain, thyrotoxicosis, and tremors. Propranolol has been around for nearly six decades and is the 63rd most prescribed medication in the US.
Like other beta-blockers, Propranolol slows your heart rate and thus makes it easier to circulate blood in your body’s blood vessels, which will lower your blood pressure.
Both standard Propranolol tablets and extended-release capsules will yield first blood pressure lowering effects after about 30 minutes of taking the medication. However, it’s only after one week of continuous treatment that Propranolol will reach its full effect.
The effect of standard-release Propranolol peaks within 1 to 1½ hours of taking a capsule and will last for about 5-6 hours. When using extended-release capsules, it will take six hours before Propranolol blood levels reach their highest point and the overall effect of one capsule lasts for about 24 hours.
The active ingredient is propranolol hydrochloride.
Inactive ingredients include lactose, magnesium stearate, microcrystalline cellulose, and stearic acid.
Please note, the inactive ingredients may vary across different brands of Propranolol.
Propranolol causes a severe allergic reaction in people on rare occasions. If you have previously taken propranolol, and experienced symptoms of a severe allergic reaction, please do not take them again and let your doctor know. Facial swelling, a rash, dizziness, and trouble breathing are signs of a severe allergic reaction to propranolol. Get emergency medical help as soon as you notice any of these symptoms.
The dose of Propranolol suitable to you will depend on your condition and severity of symptoms. The usual starting dose for adults with hypertension is 80 mg taken twice per day. If the desired blood pressure-lowering effect is not reached within a month, your GP may decide to raise your dosage up to 160 mg twice per day. For conditions other than hypertension, different dosages apply, so make sure to follow your doctor's instructions.
Always take Propranolol as instructed by a doctor or pharmacist. Standard release tablets are taken once a day, swallowed whole with a glass of water. You can take them with or without food, as Propranolol doesn’t irritate the stomach. Extended-release capsules at first are best taken in the evening before bedtime since they can make you feel dizzy. Once your body is accustomed to the medication or if you don’t feel dizzy from the start of treatment, you can take the capsule in the morning. Generally, for the best effect, you should take Propranolol regularly at the same time each day.
If you are thinking of stopping Propranolol treatment, first consult with your doctor. It’s recommended to gradually wean off Propranolol, as a sudden stop can cause unpleasant and even dangerous cardiovascular side effects. It will take about 2-4 weeks to gradually phase out your Propranolol treatment.
Missing a dose isn’t a cause for concern. Just take your next dose at the scheduled time. Never take a double dose to make up for a missed one.
Overdosing on Propranolol can slow your heart rate and cause breathing difficulties, dizziness and tremors. Each person has a different overdosing threshold, so it cannot be generalized at what dosage you are likely to experience overdosing effects. So, if you think you have accidentally overdosed on Propranolol, seek medical help right away.
Like all medications, Propranolol may cause side effects in some patients, in particular during the initial treatment stage, when your body is still getting used to Propranolol. Many of those side effects disappear after several weeks of treatment.
Common mild side effects occurring in more than 1 out of 100 patients include:
These side effects are most often observed during the first two weeks of treatment and normally only last a few days. If they last longer or make you feel uncomfortable, talk to your doctor.
Serious side effects are rare but can happen. If you experience any of the following side effects, you’ll need to seek immediate medical help.
For a comprehensive list of Propranolol side effects, see the manufacturer’s leaflet inside the packet.
Do NOT take Propranolol if you:
Before taking Propranolol, tell your doctor if you are/have:
Before starting a Propranolol treatment, tell your GP about all medication you currently use or plan on using at the same time as the Propranolol treatment. Known interactions with other drugs include:
Consuming alcohol can increase Propranolol’s blood pressure-reducing effect, resulting in dizziness. Therefore, alcohol consumption is best avoided or minimized during Propranolol treatment, especially in the first few weeks of treatment.
There are many different types of hypertension medications, including various beta-blockers, ACE inhibitors, calcium channel blockers, diuretics, and angiotensin II receptor blockers (ARB). Depending on your blood pressure levels, accompanying symptoms, other medical conditions, or medications you may be taking and your age, your doctor will evaluate and decide which hypertension medication will offer you the best balance of benefits and risks. Sometimes it will be a combination of drugs. Typically, Propranolol is considered a particularly suitable choice for treating hypertension if the patient has abnormal heart rhythms.
Taking Propranolol regularly for treating high blood pressure doesn’t require lifestyle changes. However, there are several lifestyle improvements you can make to help Propranolol reduce blood pressure and boost your overall well-being. Cut back on fatty foods and limit your salt intake to 6g per day or lower. Eat plenty of fruits and vegetables, and always go for whole grains and lean meats. Exercising regularly will keep the heart and blood vessels in good condition and also contributes to relieving stress. Mental stress is a major cause of hypertension, so try avoiding it. Limit alcohol consumption as much as possible and, if you are currently smoking, it’s time you quit.
Especially during the first couple of weeks of taking Propranolol or if you took a larger dose, you might feel a bit dizzy. In the event that this happens, it’s recommended to not drive a car or other vehicle.
Yes. Treating social and performance anxiety is one of Propranolol’s medical uses. How quickly Propranolol works for anxiety differs from person to person, but its effect usually starts within one hour of taking the drug. Likewise, how long Propranolol lasts for anxiety varies with each dosage and person. Generally, though, the effect will last for 5-6 hours. Your doctor can help you find the right dosage.
Yes. Propranolol can be prescribed for long-term migraine prevention. Propranolol for migraines is available through Medzino here.
If you have asthma, the use of Propranolol is advised against and most likely won’t be prescribed by doctors, since the medication could make your asthma worse.
Disclaimer: This is not medical advice. You and your physician will determine if and how you should take any medication prescribed to you following a medical consultation.
Propranolol is one of the 1st generation beta-blockers and has been in use since the 1960s. Initially intended for treating high blood pressure, the drug eventually came to be used for many other purposes, including heart issues, performance anxiety, tremors, and the symptoms of hyperthyroidism. This wide range of medical applications makes Propranolol one of the most frequently prescribed medications in the United States.
Propranolol is a 1st generation beta-blocker that originally was marketed as Inderal but is now available in generic form. Propranolol has been around since the 1960s and today has a wide range of uses. The British scientist, J. W. Black, who first developed propranolol, received the 1988 Nobel Prize in medicine for his work.
Propranolol (generic Inderal) is a beta-blocker available by prescription that is used to lower blood pressure in patients with hypertension. The drug typically can also be used to treat other health conditions, such as heart rhythm problems, heart attack prevention, anxiety, and tremors. Propranolol has been in use for almost sixty years and is one of the first beta-blocker medications. It ranks among the top 100 most prescribed drugs in the US and European markets.
High blood pressure, the technical term is hypertension. High blood pressure is a common long term condition people can experience. It does not usually have noticeable symptoms. If left untreated or uncontrolled it can become dangerous as it increases your chances of certain conditions.
When you exercise, your heart rate increases and can vary depending upon the intensity of the exercise you do. Therefore, it is often more relevant to measure your resting heart rate - the number of times your heart beats while you are completely at rest.
While there are many medications that treat anxiety, many of them can be highly addictive or have unwanted side effects such as drowsiness. This is why many people look for alternatives to the benzodiazepines that are usually prescribed for anxiety. Atenolol, and other beta-blockers are often prescribed as non-addictive medications for anxiety.
Grapefruit and grapefruit juice can interact with Amlodipine. Amlodipine is broken down by enzymes (CYP3A4) in the lower intestine. People have different levels of these enzymes in their body, so eating grapefruit can affect people differently. Eating grapefruit can block the action of these important enzymes. This causes the drug to stay around for longer, which may allow too much Amlodipine to enter your bloodstream. Higher levels of Amlodipine mean stronger effects and a higher likelihood of side effects.
Whilst it’s highly effective, Amlodipine also has many side effects. These include dizziness, headaches, swelling and stomach pain. A rare side effect of Amlodipine is weight gain, therefore the risk is low. Many factors that may increase your risk of high blood pressure i.e. high-calorie diet, may contribute to increased weight gain when taking Amlodipine. If you feel Amlodipine is causing you to gain weight, you may want to look into alternative blood pressure medication.
Amlodipine (Norvasc) is prescribed to treat high blood pressure. It does this by opening up the blood vessels to improve your blood flow. However, it can also come with some unpleasant side effects. The most common of these are nausea, headaches, mild swelling and stomach pain. To avoid these side effects, you might be looking for an alternative.
Heart disease is also referred to as coronary artery disease. In the US, heart disease triggers 735,000 heart attacks each year and causes the death of more than 630,000 Americans. 7 million Americans have suffered a heart attack at some point in their life according to the American Heart Association. Heart disease is very common and is known as the silent killer. You must know what factors can contribute to the increased risk of heart disease.
Be honest. Sleeping in on the weekend doesn’t count, we are talking about a regular sleep schedule aligned with your body’s internal clock.
Chronically high blood pressure puts you at risk of developing several diseases and dying early. High blood pressure causes a lot of damage because of the damage done to blood vessels particularly arteries. Healthy blood vessels are essential for every organ to function properly so high blood pressure can potentially damage many organs including your heart, eyes and kidneys.
While Lisinopril is very effective at reducing blood pressure and helping the heart recover from cardiac arrest, it can react poorly when combined with alcohol. Lisinopril works by lowering your blood pressure through a relaxation of your blood vessel muscles. That’s ideal for treating various heart conditions and hypertension, but when you combine it with alcohol, the effects can be disastrous. That is because alcohol lowers your blood pressure as well, so your blood pressure could become dangerously low.
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