The most common side effects include:
- Local skin pallor
- Redness to the application site
- Mild burning to the application site
Rare side effects include:
- Change in temperature sensation
- Swelling or itching of the application site
Rarely, people may have an allergic reaction ranging from itching, stinging, blistering and anaphylaxis. This has been rarely reported.
Lidocaine/Prilocaine cream should not be applied to open wounds, near the eyes, or in the ears. Allergic reactions may occur.
There is a low risk of drug interactions when a small amount of lidocaine is applied topically. However, caution should be used if you are taking anti-arrhythmic drugs (such as tocainide or mexiletine).
Allergy to local anesthetics (such as procaine, tetracaine, benzocaine, lidocaine) or any other ingredients in EMLA.
Is Lidocaine/Prilocaine Cream safe in pregnancy?
There are no adequate and well-controlled studies in pregnant women. Lidocaine/Prilocaine Cream should only be used during pregnancy if clearly needed and prescribed by a doctor.
Is Lidocaine/Prilocaine Cream safe during breastfeeding?
Avoid using Lidocaine/Prilocaine Cream while breastfeeding, as a small amount may be present in breast-milk.