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Sertraline is a prescription drug that has a popular off-label use as a treatment for premature ejaculation. In fact, it’s recommended by the American Urological Association for that purpose.
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Written by Dr Yasmin Aghajan, MD
Information last reviewed 06/21/19
Premature ejaculation (PE) is defined by quick ejaculation (1-2 minutes), inability to delay or control ejaculation, and distress about the condition. There are several options for treatment. The first choice for treatment is Sertraline. Other options include numbing cream, such as Lidocaine/Prilocaine (EMLA).
Sertraline is a medication of the selective serotonin reuptake inhibitor (SSRI) class. It works by increasing the amount of serotonin that neurons can use. Although it can be used for premature ejaculation, it is most commonly used to treat depression, anxiety, posttraumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), and social anxiety disorder.
Sertraline is approved in the treatment of depression, PTSD, OCD, and panic disorder. It is prescribed off-label for premature ejaculation.
For men who suffer from premature ejaculation, several studies verify that regular use of Sertraline can increase the average amount of time it takes for ejaculation to occur during sexual intercourse; however, it can take up to several weeks for the treatment to be fully effective. Statistics reveal that men who took a daily 25mg oral dose of Sertraline, gradually increasing the dose to 100mg over a period of six weeks, on average, enhanced their ejaculatory interval by approximately 16 minutes. Correspondingly, reports of sexual satisfaction for the men, and their partners, also increased as a result of using Sertraline.
In most cases, it can take several weeks before the full effects of Sertraline are felt in delaying premature ejaculation. Using evidence from respective studies, most men experienced the most significant improvement in ejaculation latency after four weeks of treatment, although its effects can be felt in the first use.
The active ingredient in Sertraline is sertraline hydrochloride (25, 50, or 100mg).
The inactive ingredients include: dibasic calcium phosphate dihydrate, D & C Yellow #10 aluminum lake (in 25 mg tablet), FD & C Blue #1 aluminum lake (in 25 mg tablet), FD & C Red #40 aluminum lake (in 25 mg tablet), FD & C Blue #2 aluminum lake (in 50 mg tablet), hydroxypropyl cellulose, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, sodium starch glycolate, synthetic yellow iron oxide (in 100 mg tablet), and titanium dioxide. Inactive ingredients may vary by manufacturer.
The proper dosage for Sertraline for premature ejaculation is between 50mg and 200mg per day. It should be increased as needed every four weeks. There is no dosage adjustment for kidney disease. Do not stop taking Sertraline before talking to your doctor.
Sertraline can either be used on a regular basis, or as and when it is needed, to effectively treat premature ejaculation. Depending on the individual case and symptoms, dosage may range from 25 to 200 milligrams. There is no customary approach when treating with Sertraline; therefore, it is highly recommended that you follow your doctor’s instructions and do not take more than the prescribed amount.
There is an FDA warning for this class of medication that it can increase the risk of suicidal thoughts and behavior in young adults. Sertraline may cause increased bleeding, impair cognitive function (use caution while driving or operating machinery), narrow-angle glaucoma in susceptible individuals, and serotonin syndrome, which is a potentially life -threatening condition when SSRIs are used in combination with other serotonin agents. Always tell your doctor what medications and supplements you are taking. SSRI medications may cause low levels of blood sodium which could be life-threatening.
The most common side effects were insomnia (20%), dizziness (12%), fatigue (12%), drowsiness (11%), nausea (26%), diarrhea (20%) and dry mouth (14%).
Less common side effects include palpitations, agitation, malaise, sweating, decreased libido, erectile dysfunction.
Sertraline is known to have interactions with the following medications:
Sertraline is contraindicated in patients taking monoamine oxidase inhibitors (MAOIs), and in patients with an allergy to Sertraline or its other ingredients.
Sertraline was approved in 1991, and is one of the most prescribed medications in the United States.
Sertraline, or Zoloft, is manufactured by Pfizer. However, it is available as a generic medication as well.
Although Sertraline does not cause users to become physically dependent on the medication, due to it being a commonly-prescribed remedy for other issues, it can often become psychologically addictive, depending on what it is used for. This type of addiction has been known to occur in users treating symptoms of depression, as the medication can generate a feeling of improved well-being; conversely, not having access to the drug can cause feelings of anxiety, frustration or depression, as well as physical symptoms such as nausea, hand tremors and insomnia.
Research suggests that Sertraline could damage male fertility by reducing the quality and concentration of sperm. Therefore, treatment with Sertraline for men who are trying to start a family is not recommended.
Disclaimer: This is not medical advice. You and your physician will determine if and how you should take any medication prescribed to you following a medical consultation.
Viagra and its generic form, sildenafil, are prescribed to millions of men every year to treat erectile dysfunction (ED). The drug was first approved as an ED treatment in 1998 — after initially having been developed in the 1980s as a hypertension medication — and marketed by Pfizer. Since about half of all men will have to cope with erectile problems at some point (mostly in their older years), Viagra quickly became a popular ED medication.
As is the case with many sexual health issues, people who suffer are often reluctant to talk about it. It is reported that sexual dysfunction of some sort is experienced by 31% of men at some point in their lives, but some men are afraid to speak about their ejaculation problems. Fortunately, ejaculation related problems are often treatable.
An erogenous zone is a place or area of your body that is highly sensitive to touch and can trigger a sexual response, such as getting you aroused, giving a goosebumps feeling or other pleasant sensations. The stimulation occurs because of a high density of nerves in these places. The more nerves extend into that part of your skin, the stronger the sensual response will be.
Lidocaine-prilocaine is a widely used anesthetic commonly used in root canals or dental surgical procedures. The cream is regularly used to numb your gums before the dental procedure. It works by reducing the sensitivity after application to the skin.
If you have difficulties with holding your orgasm or involuntary ejaculate within one minute of vaginal intercourse, this, from a scientific point of view, qualifies as premature ejaculation (PE). Some 30% of men have to deal with this issue at least for a certain period of their life, while for others it can be a life-long problem. Now, we say “problem”, but in fact, in medical terms, there’s nothing unhealthy about coming too early. Neither does it keep you from producing healthy offspring. It’s really only a problem in psychological terms. You and/or your partner would like to enjoy sexual intercourse for a little. Many men with PE are disappointed in their sexual performance, which may prevent them from dating or cause anxiety. Today’s easy access to porn and generally inflated expectations of male virility worsen the problem.
Premature ejaculation is when ejaculation occurs earlier than desired during sexual intercourse. I can cause stress and anxiety and even put a strain on the relationship. However, there is no need to worry. Lidocaine and prilocaine cream has been designed to desensitise the penis and help you last long during sex. This FDA approved cream can be prescribed by the doctors to help make your sexual experience more enjoyable.
Benzocaine and Lidocaine are essentially the same and have the same mechanism of action but they differ slightly. Premature ejaculation is when ejaculation occurs sooner than desired during sex. Premature ejaculation should not be a cause for worry, however, can be frustrating and make sex less enjoyable.
Sertraline is an SSRI class (selective serotonin reuptake inhibitor) antidepressant that’s approved by the U.S. FDA and available on prescription to treat a range of mental disorders. It’s been used for treating clinical depression and other conditions since 1991 and at first was marketed by Pfizer as Zoloft.
Sertraline and fluoxetine both are prescription antidepressants of the SSRI class (selective serotonin reuptake inhibitor). Both medications are available as generic versions, but the most popular trade names are Zoloft (Pfizer) for sertraline and Prozac (Eli Lilly & Co) for fluoxetine.
More commonly known as Zoloft, which is the trade name Pfizer uses, sertraline is an antidepressant that is widely used as a treatment for depression, anxiety disorder, post-traumatic stress, and obsessive compulsive disorder. Over 35 million prescriptions for sertraline are issued in the United States annually.
Sertraline is a selective serotonin reuptake inhibitor (SSRI), which is a class of drugs that also includes Prozac and Paxil. SSRI increases the amount of serotonin in the brain. Serotonin is a neurotransmitter responsible for sending signals between brain cells, in particular, signals associated with positive emotions.
Sertraline — also known under Pfizer’s trade name Zoloft — is a prescription antidepressant that is used to treat depression, anxiety disorder (such as panic and social anxiety), post-traumatic stress, and obsessive-compulsive disorder. The usual daily dosage can vary from 50mg to 200mg, depending on treatment use and duration.
Premature ejaculation is a common problem in the male population, with nearly 30 percent of men reporting problems with controlling and holding back ejaculation for as long as they’ want to. Doctors typically regard an ejaculation as premature if it happens against the man’s will and in under one minute of vaginal intercourse.
Premature ejaculation is the clinical term for an involuntary, early male orgasm that happens within the first 1-2 minutes of sexual intercourse. For reference: the average time of sexual intercourse for most couples is about five minutes and only very few make it past ten minutes.
Doctors define premature ejaculation as a male orgasm that involuntarily occurs within the first minute of sexual intercourse. In plain terms this means that if you frequently can’t help coming right after you’d just started sex you are suffering from premature ejaculation.
Sexual intercourse on average lasts about 5 ½ minutes, with the high side of the range being around 10 minutes. There are many causes why for some couples sex may be considerably shorter than 5 minutes, depending on location, mood and time of the day.
The clinical definition of premature ejaculation, as most experts would define it, is an involuntary male orgasm that happens within 60 seconds of vaginal intercourse. The premature ejaculation topic is less researched for anal sex, but it’s safe to assume that the same time definition applies.
Premature ejaculation in clinical terms refers to men getting an orgasm — the discharge of semen — during sexual intercourse earlier than they would like. There is no definition for how early that is, since some men may choose to come thirty or sixty seconds into the intercourse.
Ejaculations are called premature if they last less than 1.5 minutes. On average, ejaculations are delayed 7 minutes during intercourse. An estimated one in five men experiences an issue with early ejaculation during his life. But it’s rare that physical conditions such as inflammation are the underlying cause. In most cases, premature ejaculation is linked to underlying performance anxiety or another mental issue.
It sounds simple: you grab a ruler, align it against your penis and read the number. But not so fast, there’s a correct way to measure your penis. If the angle of the ruler is off or your starting and endpoints are a bit too liberal, you may be doing it wrong. Here’s what you need to know to avoid cheating yourself.
Unfortunately, the answer to that question is: yes. In the medical world, it’s not described as ‘breaking’, because there are no bones in the penis. But the ‘penile fracture’ can indeed happen during sex. It’s most likely when the penis is bent severely and the tunica albuginea (the penis membrane) ruptures. As a consequence, blood that flows through the corpora covernosa during an erection begins to leak into the surrounding tissues.
Size matters; or does it? According to a survey by the American Psychological Association, 85% of women are actually satisfied with their partner’s penis size. Only 55% of men felt the same way. Similarly, one study asked women to read arousing stories where male characters either had small, medium or large penis sizes. The researchers found that there were no differences in sexual arousal based on penis size.
Almost half of men (45%) believe their penis is too small, yet a study of 15,000 men found that the average size of the flaccid penis was 9.16 cm and that of an erect penis was 13.12 cm. These are averages though. In reality, penis size varies by around 3 cm either end of the estimates.
It’s important to stay well informed when it comes to all things sexual health. There is a lot of misinformation circulating about average penis size, sexual performance, and erectile dysfunction. Some men, for example, believe that women are only attracted to man large packages. Yet, 85% of women in partnerships said they were satisfied with their partner’s penis size. Keep up communication with your sexual partner to find out more about their preferences.
There are many reasons why men lose some of the sensation in their penis over time. Loss of sensitivity is natural with advancing age due to underlying blood vessel changes. In a survey, at least half of men over the age of 57 years reported sexual dissatisfaction. But before you content with a numb penis, you should rule out a series of physical conditions.
Premature ejaculation can be a difficult topic to talk about. Men often shy away from a conversation about their issues because of fear of being stigmatized or made fun of. But it’s actually the most common sexual dysfunction in men. According to estimates, up to 39% of men worldwide experience premature ejaculation at some point in their lives.
Wanting to know how you can eliminate any anxieties in the bedroom? Looking to boost comfort and fun for you and your partner? Here are 10 top tips for changing your home to have a better sex life.
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