Enalapril vs Enalipril with Hydrochlorothiazide
Medzino offers both Enalapril and Enalapril in combination with Hydrochlorothiazide (known by the brand name Vasoretic). Hydrochlorothiazide is a diuretic (water pill), and when combined with Enalapril, works better to lower blood pressure than either medication alone. On average, Hydrochlorothiazide combined with Enalapril can lead to an additional 10 point reduction in mean blood pressure. The effect is dose dependent.
Hydrochlorothiazide is a type of thiazide diuretic and works to reduce the amount of water in the body by increasing urination. Reducing the amount of water in the body also reduces the amount of total fluid inside the blood vessels. This, in turn, reduces the pressure inside the vessels and thereby lowers blood pressure.
Hydrochlorothiazide is used to treat high blood pressure alone or in combination with other medications such as Enalapril. It is also used to treat edema (fluid retention), which can be caused by different conditions such as heart failure or cirrhosis of the liver.
While it is commonly prescribed as a first-line agent for high blood pressure, Hydrochlorothiazide may not be appropriate for some patients and should be generally avoided by individuals with the following conditions:
- Anuria (an inability to urinate)
- Sulfa drug allergy
- Electrolyte abnormalities such as low sodium, low potassium, low calcium or low magnesium
- Gout or hyperuricemia (high levels of uric acid in the blood)
- Hypoglycemia (low blood sugar)
- Use with caution and only after discussion with your doctor if you have kidney disease, liver disease or systemic lupus erythematosis (SLE)
Multiple medications or supplements may interact with Hydrochlorothiazide. Please consult your doctor or pharmacist if you are taking any medications or herbal supplements before taking Hydrochlorothiazide.